Your Endocannabinoid System: Simplified

by Stephanie Burner October 16, 2018

Wait, we have an endo-what? And we produce cannabinoids? Where have I been?! These were some of my questions when I first heard tell of the remarkable endocannabinoid system or ECS. I felt so ignorant and like I had been living under a rock, but I was also excited and intrigued! I wanted to know more so I read what I could and talked with those more familiar with the subject, as I was utilizing and selling CBD oil and wanted to be informed. Who knows about this and how long have they known? What IS IT?! What role does it play and how can it affect our health?

Well, I discovered I was not alone – many people, all over the States were being introduced not only to CBD but to the ECS as well, including medical doctors, nurses, pharmacists, etc. So, that brought up another question. Why don’t those in the medical field know about this system?! As it turns out the ECS is rarely taught in current programs at U.S. med schools. A mere 13.3% of medical schools surveyed by David B. Allen, M.D., teach this science to future doctors and medical professionals. This is silly and breeds ignorance. But all along, government-funded studies (in Universities!) were/are being conducted on uses for medical marijuana and the results and findings had/have been vastly underreported in the mainstream media. Until now. The advent and press coverage of CBD has provided a much-needed platform for the ECS to be discussed. We believe it’s extremely important for the public to be aware of this (not-so) new science and we’ll start with a quick overview.

The endocannabinoid system is multi-functioning, multi-layered and impressive to say the least. Currently, it is best recognized for providing homeostasis. Homeostasis is another term for harmony or balance, a feeling of being “just right”. Our bodies do not favor extremes, like high (or low) blood pressure, or being too hot or cold; the ECS regulates these conditions at the cellular level to keep us comfortable and healthy.

Discovered by Miles Herkenham in 1990, the ECS consists of three components:

  • Cannabinoid Receptors
    • CB1 receptors are found in high levels in many regions of the brain and in lower amounts throughout the rest of the body. These moderate the psychoactive effects of cannabinoids and terpenes. Interaction with THC demonstrates the ability of the CB1 receptors.
    • CB2 receptors are fewer and found mainly in immune cells and densely throughout the gut. These play a very large role in maintaining homeostasis.
  • Endocannabinoids
    • Endogenous cannabinoids, meaning those produced in the body; found in breast milk
      • Anandamide – the most-helpful “Bliss Molecule” interacts with CB1 receptors; CBD slows the breakdown of anandamide. Increased levels equal less anxiety in most cases, as well as appetite regulation, sleep pattern regulation, mood regulation, and decreased sensitivity to pain.
      • 2-AG – is present in both the immune and central nervous system where it regulates immune and nerve function, signaling for and sending immune cells to promote healing and reduce inflammation.
  • Metabolic Enzymes
    • These enzymes work to break down structures that are no longer needed, produce new cells and maintain existing ones until they are ready to make their exit. Enzymes also aid in nutrient absorption and distribution and are also in charge of detoxing. We would be hurting without these!

With only a small amount of information, I hope you can see why it is imperative that we become familiar with this system and the latest findings. Public access and education are needed, and it can start with us! Just think of how far we’ve come without knowing, and how far we may go now that the word is out. I look forward to writing more on this subject and I hope you’ll read along as we explore the ECS. Comment below and please share this article!

Stephanie Burner
Stephanie Burner


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CBD & Drug Testing: Can HEMP CBD cause me to fail?
CBD & Drug Testing: Can HEMP CBD cause me to fail?

by Stephanie Burner February 06, 2019

Can one fail a drug test using hemp CBD oil?

Yes, is the long and short of it but there are options to avoid this! Selecting the product that fits your needs is key so do your research or visit a trusted retailer for direction. Remember too, that sourcing and quality matters. One study revealed that up to 70% of online CBD products are mislabeled (1). Yikes! We’re not saying don’t buy online but be a conscious consumer for your health. Luckily, there are lots of local options with educated employees and why not utilize the free advice for your purchases?!

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What if CBD isn't working for me? Troubleshooting Guide!!
What if CBD isn't working for me? Troubleshooting Guide!!

by Stephanie Burner January 10, 2019

Honestly, the idea of CBD not working for someone is hard for me to hear. I want people to be well and it seems unfair! Though not often, it does come up and we are paving the road to greater understanding when we share our genuine experiences. It is always a good idea to be honest about how something is or isn’t working in your body! It’s easy to become very frustrated when you try CBD every which way and feel nothing. Or you find relief and then the body stops responding the same way it did months ago, at the same dose. Because we are all unique biologically and because things can change at a moment’s notice on a cellular level, this is normal and to be expected so don’t give up on yourself or your Endocannabinoid System. Below, I offer some suggestions for those who have experienced a lackluster effect from CBD.

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Supporting the System: What is Endocannabinoid Deficiency?
Supporting the System: What is Endocannabinoid Deficiency?

by Stephanie Burner December 10, 2018

Endocannabinoid deficiency is exactly what it sounds like – one’s body lacks endocannabinoids or the proper functioning of receptors creating a weakened system. It’s very real and backed by decades of research. When supplementing with hemp products, consumers really ought to know how to support and optimize the system! There’s a bit of ground to cover but I’ll keep it simple.

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